UORSY Screening Compounds

last updated April 2017

Our screening compound library comprises more than 600,000 compounds. This collection has resulted from our 15 years efforts in supporting drug discovery through high-throughput screening. We offer the compounds assembled from the in-house made building blocks utilizing the developed and thoroughly optimized reactions including popular in medicinal chemistry amide bond formation, arylation and alkylation. In the collection design, we have widely exploited a convergent synthesis approach that furnished high diversity of the chemical structures.

More than 85% of our compounds have drug-like physicochemical profiles, and more than 35% – lead-like profiles.

   

We also offer three diverse sets of screening compounds that cover broad chemical space:

  • 20k (19919);
  • 10k (9932);
  • 5k (4963).

The diversity increases from the largest to the smallest set. Each library is filtered from Pan-Assay Interference and “boring chemistry” substances to ensure its quality.

Physicochemical profiles of UOrSy diverse screening sets are shown on histograms below:

   

UOrSy screening libraries are available in stock and could be delivered within 2 weeks in any customer-preferred format: as powders, dry films or DMSO solutions formatted in vials, 96 or 384-well plates. All compounds have a minimum purity of 90% assessed by 1H NMR; analytical data is provided.

For more information, please contact us at screenlibs@uorsy.com

Your questions and requests are always welcome!
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