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UORSY Hedgehog Pathway Modulators

Hedgehog pathway (Hh) is known to play role in cell development and survival. Inhibitors of proteins, involved in Hh regulation represent a relatively new and small class of anti-cancer drugs.¹

Physicochemical profiles of UORSY hedgehog pathway modulators:

160<MW<500; 1<HbA<7; 0<HbD<3; 0.25<logP<5; RotBonds≤8; TPSA<144.

UORSY hedgehog pathway modulators is available as powders, dry films or DMSO solutions. All compounds have a minimum purity of 90% assessed by ¹H NMR; analytical data is provided.

For more information, please contact us at screenlibs@uorsy.com

¹Wahid, M.; Jawed, A.; Mandal, R. K.; Dar, S. A.; Khan, S.; Akhter, N.; Haque, S. Crit. Rev. Oncol. Hematol. 2016, 98, 235–241.