Hedgehog pathway (Hh) is known to play role in cell development and survival. Inhibitors of proteins, involved in Hh regulation represent a relatively new and small class of anti-cancer drugs.1
Physicochemical profiles of UORSY hedgehog pathway modulators:
160<MW<500; 1<HbA<7; 0<HbD<3; 0.25<logP<5; RotBonds≤8; TPSA<144.
UORSY hedgehog pathway modulators is available as powders, dry films or DMSO solutions. All compounds have a minimum purity of 90% assessed by 1H NMR; analytical data is provided.
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1Wahid, M.; Jawed, A.; Mandal, R. K.; Dar, S. A.; Khan, S.; Akhter, N.; Haque, S. Crit. Rev. Oncol. Hematol. 2016, 98, 235–241.
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