• Home page
• Fragments and Targeted libraries
• Polyhydroxy Compounds

UORSY Polyhydroxy Compounds

Hydrogen bonding, one of the major types of protein-ligand interactions, commonly occurs between polar residues especially those with hydroxyl moieties. Consequently, polyhydroxylated fragments are frequently found in natural and natural-like compounds such as oxopolyene macrolide antibiotics, polyketide-derived natural products, and statins with 1,2- or 1,3-diol subunits.

Considering the above-mentioned observations, we have created a conceptually new set of polyhydroxy compounds. The set comprises compounds bearing at least two hydroxyl groups, which are directly attached to sp³ hybridized carbon atoms.

We split the resulting library into 2 subsets, available upon request:

• one-week delivery (139 compounds)
• three-weeks delivery (16,911 compounds)

For more information, please contact us at screenlibs@uorsy.com