UORSY Polyhydroxy Compounds

Hydrogen bonding, one of the major types of protein-ligand interactions, commonly occurs between polar residues especially those with hydroxyl moieties. Consequently, polyhydroxylated fragments are frequently found in natural and natural-like compounds such as oxopolyene macrolide antibiotics, polyketide-derived natural products, and statins with 1,2- or 1,3-diol subunits.

Considering the above-mentioned observations, we have created a conceptually new set of polyhydroxy compounds. The set comprises compounds bearing at least two hydroxyl groups, which are directly attached to sp3 hybridized carbon atoms.

We split the resulting library into 2 subsets, available upon request:

  • one-week delivery (139 compounds)
  • three-weeks delivery (16,911 compounds)

For more information, please contact us at screenlibs@uorsy.com

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