Selective androgen receptor modulators (SARMs) are a class of androgen receptor ligands, which possess advantages of specificity and selectivity of action.
To create our SARMs library we performed the analysis of literature data and generated a database of more than 20 000 structures with SARMs-related activity. All structures were divided into 5 clusters according to main chemotypes. Flexible molecular docking against known structures, utilizing our in-stock compound collection, was performed.
Physicochemical profiles of UORSY selective androgen receptor modulators:
200<MW<500; 2<HbA<7; 0<HbD<4; -1.0<logP<6; 0<Fsp3<0.63; 1<RotBonds<9, TPSA<135.
UORSY Selective Androgen Receptor Modulators Library is available in stock and could be delivered within 2 weeks in any customer-preferred format: as powders, dry films or DMSO solutions formatted in vials, 96 or 384-well plates. All compounds have a minimum purity of 90% assessed by 1H NMR; analytical data is provided.
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