Lead-like molecules have been considered as a better starting point for drug discovery projects compared with drug-like molecules. Our lead-like subsets are diversity selections of 35, 20 and 10 thousand from the pool of our lead-like compounds.
Physicochemical profiles of UORSY lead-like compounds:
200<MW<350; HbA≤8; HbD≤4; -1<logP<3; 14<HAC<26; RotBonds≤7; 40<TPSA<120; 0.25<Fsp3<0.95; AromRing≤3.
UORSY lead-like compounds are available in stock and could be delivered within 2 weeks in any customer-preferred format: as powders, dry films or DMSO solutions formatted in vials, 96 or 384-well plates. All compounds have a minimum purity of 90% assessed by 1H NMR; analytical data is provided.
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